Caprine Arthritis Encephalitis (CAEV)/Maedi-Visna (MVV)

Maedi-visna virus (MVV) infection of sheep is characterized by slowly progressive arthritis, pneumonia, mastitis and encephalomyelitis. The causative agent of the disease is a virus classified as lentivirus, a subgroup of retroviruses. MVV infection is found all over the world.

This classification also includes caprine arthritis encephalitis virus (CAEV), which manifests itself in adult goats mainly in the form of severe arthritis of the carpal joint ("big knee").

Animals with CAEV become emaciated despite an intact appetite, and show poor milk yield. Serologic surveys show that CAEV is widely disseminated in goat herds on different continents.

By far, the most important source of infection, however, is the milk of positive animals. In fact, if the kids are fed with communal milk from the herd, all the kids can be infected by just a single positive goat. An effective vaccination does not exist. For this reason, eradication programs are based on colostrum deprivation, separation and serological detection of infected animals.

Specific antibodies in serum for both diseases can be measured by the same ELISA.
Caprine Arthritis Encephalitis/Maedi-Visna

Testing Solutions†

IDEXX CAEV/MVV Total Antibody ELISA Tests

Availability/Distribution: Outside the U.S.

The IDEXX CAEV/MVV ELISA Tests are enzyme immunoassays for the detection of antibodies against Caprine Arthritis and Encephalitis virus (CAEV) and Maedi-Visna virus (MVV) in serum, plasma and milk samples of goat and sheep.

 

CAEV/MVV Total Ab Screening Test Informational Sheet  

 

  • Runs on multiple sample types: serum, plasma and milk, for a simple streamlined process
  • Promotes efficiencies with modern kit format: easy to use, with ready-for-use reagents
  • Provides flexible planning: short (90 minutes) and long (overnight) protocols
  • Allows high sample throughput: adapted to automation for cost and time savings
  • Offers easy data management when used with xChek® software

IDEXX CAEV/MVV Total Ab Screening Test:

Part Number: CVT1135T (2/strip)
Part Number: CVT1131T (10/strip)

  • 2 plates (strips) or 10 plates (strips)
  • serum and milk confirmation
  • ready-to-use reagents (caprine, ovine)

 

IDEXX CAEV/MVV Total Ab Verification Test:

Part Number: CVT1145T

  • 2 plates (strips)
  • screening of serum, plasma and milk samples of goats and sheep
  • monophasic kit
  • short protocol (caprine, ovine)
 

IDEXX MVV/CAEV p28 Ab Screening Test

Availability/Distribution: Outside the U.S.

The IDEXX MVV/CAEV p28 Ab Screening Tests is based on the use of an immunogenic peptid of a transmembrane protein (TM, ENV gene) and of the recombinant p28 protein, which enters into the composition of the viral capsid (GaG gene). Anti-p28 antibodies can appear slightly later than the antiviral envelope protein antibodies. The use of this very stable protein allows the serological detection of a very wide spectrum of serological variants.

IDEXX MVV/CAEV p28 Ab Screening Test:

Part Number: P00303-10

  • 10 plates
 

IDEXX MVV/CAEV p28 Ab Verification Test

Availability/Distribution: Outside the U.S.

The IDEXX MVV/CAEV p28 Ab Verication Test is based on the use of an immunogenic peptid of a transmembrane protein (TM, ENV gene) and of the recombinant p28 protein, which enters into the composition of the viral capsid (GaG gene). Anti-p28 antibodies can occur slightly later than that of anti-viral envelope protein antibodies.

IDEXX MVV/CAEV p28 Ab Verification Test:

Part Number: P00302-5

  • 5 plates (strips)
 

Pourquier® AGID CAEV p28 Ab Test

Availability/Distribution: Outside the U.S.

The Pourquier AGID CAEV p28 Ab Test detects antibodies to the CAE viral capsid protein (p28) using the agar gel immunodiffusion (AGID) technique.

Pourquier AGID CAEV p28 Ab Test:

Part Number: P00310

  • 120 tests
  • supplied with agar gel bottles
 

† Not all products are available and/or registered in every country.