IDEXX ProCyte Dx® Haematology Analyser

Three cutting-edge technologies working together
Laser flow cytometry, optical fluorescence and Laminar Flow Impedance™ work together to give you unprecedented accuracy, speed and precision.
Two-minute run time
Real-time answers during your patients’ visits let you share results and recommendations with clients face-to-face, while simple operation minimises time and effort.
More complete medical information
An advanced five-part white blood cell differential and absolute reticulocyte count along with validated results on 26 different blood parameters* give you with a more complete picture of each patients’ health.

The ProCyte Dx analyser connects to the IDEXX VetLab® Station Laboratory Information Management System to provide:

All your diagnostic information in one comprehensive patient report
Access to IDEXX SmartService™ Solutions: remote troubleshooting for your IDEXX VetLab® analysers that saves time and helps keep your laboratory running smoothly

See how the IDEXX Laboratories Advisory Board (U.S.) helped shape the ProCyte Dx Haematology Analyser.

Benefits
Technology
Specifications
Test Menu
How To/Resources

Real-time results at the push of a button

The ProCyte Dx® analyser takes work out of your hands and lets you get back to your patients and clients more quickly.

Load-and-go operation: Even maintenance is push-button for increased staff productivity.
Small sample size: The analyser requires only 30 µL of anti-coagulated blood. And veterinary-specific IDEXX VetCollect® EDTA tubes require only 0.5–1.5 mL of blood to get the most accurate results for every patient.
More species: Results are validated for nine species (canine, feline, equine, bovine,ferret, rabbit, gerbil, pig and mini pig) across 26 different parameters.* Simple, intuitive flagging highlights questionable results, like clumped platelets or abnormal white blood cell patterns, to indicate the need for further investigation. Other species capabilities are available.
Closed-tube sampling: There’s no sample preparation and less risk of contamination.
30-second return: Sample tube is returned in 30 seconds and available for further testing.

Smarter technology for better haematology

The ProCyte Dx® analyser employs three cutting-edge technologies to provide the most comprehensive complete blood count (CBC) available in-house.

Laser flow cytometry delivers an advanced five-part white blood cell differential. The ProCyte Dx® Haematology Analyser uses laser flow cytometry to perform a full analysis of multiple characteristics on each white blood cell, for the most accurate interpretation of all five white blood cell types.

Optical fluorescence provides a highly sensitive and accurate reticulocyte count with the use of specific fluorescent stains. Feline platelets are analysed with this method to ensure superior separation when delineating platelets and red blood cells of similar size.

Laminar Flow Impedance™ performs the fastest and most precise count of red blood cells for quick and accurate analysis. With advanced Laminar Flow Impedance technology, cells are lined up one by one to ensure each cell is characterised individually.

See larger image with captions

See larger image with captions

See larger image with captions

The process involves staining sample cells, directing laser light of 633 nm at each cell and collecting multiple angles of light scatter. Wavelengths of 660 nm and greater—denoted here in blue—are captured for very precise measurements of the cell’s nucleic content. Only the ProCyte Dx analyser offers this superior capability for highly sensitive and accurate analysis.

With advanced Laminar Flow Impedance technology, cells are lined up one by one to ensure each cell is characterised individually.

Third-party study verifies exceptional correlation¹

Recent studies comparing the ProCyte Dx analyser to the Advia® 120, the Cell-Dyn® 3700 and the Sysmex® XT-V showed unparalleled red blood cell count, haematocrit, reticulocyte count, platelet count and white blood cell count correlation.2 Results were shared at the American College of Veterinary Internal Medicine (ACVIM) forums of 2010 and 2011.

The accuracy of the ProCyte Dx analyser is demonstrated in the correlation data:

References

1.

Data on file at IDEXX Laboratories, Inc. Westbrook, Maine USA.

2.

The Advia 120 Hematology System, the Cell-Dyn 3700 Hematology Analyzer and the Sysmex XT-V Automated Hematology Analyzer are reference laboratory diagnostic instruments that analyze whole blood to provide complete blood count (CBC) results, including white blood cell differential and reticulocytes. A paper with an independent comprehensive review of all parameters can be obtained from your IDEXX sales representative.

ProCyte Dx® Analyser Specifications

Parameters (24)	HCT, RBC, HGB, MCV, MCH, MCHC, RDW, reticulocytes (absolute number and percentage), WBC, neutrophils (number and percentage), lymphocytes (number and percentage), monocytes (number and percentage), eosinophils (number and percentage), basophils (number and percentage) and platelets (number, MPV, PDW and PCT)
Species	Canine, Feline, Equine, Bovine,Ferret, Rabbit, Gerbil, Pig, Mini Pig*
Units	Conventional or SI units
Sample Size	30 µL whole blood with EDTA anticoagulant is used per evaluation. Purple-top tubes require different sample sizes (IDEXX recommends 13 mm x 75 mm IDEXX VetCollect® tubes).
Time to results	The ProCyte Dx analyser will return the sample in 30 seconds and results in approximately 2 minutes.
Reagents	System requires two reagent kits: one external and one onboard. The kits are changed at separate times.
Calibration	Performed at IDEXX. User has ability to calibrate on-site if necessary.
Quality Control	Liquid quality control available for independent analysis of analyser performance.
Sample Flow Cell	250-micron quartz cuvette using focused-flow hydrodynamics to create a single-cell stream
Operating Temperature	Instrument 15ºC–30ºC (59ºF–86ºF)
Dimensions	Width x depth x height = 32 x 41.3 x 40.3 cm
Net Weight	55 lb (25 kg)

ProCyte Dx® Haematology Analyser Test Menu

The ProCyte Dx Haematology Analyser offers a full menu of haematology parameters and prints all your IDEXX VetLab® in-house analyser results in one comprehensive report. The report provides a complete picture of your patient's health status and facilitates face-to-face communication with clients.

Results are validated for nine species (canine, feline, equine, bovine, ferret, rabbit, gerbil, pig and mini pig) across 26 different parameters. Simple, intuitive flagging highlights questionable results, like clumped platelets or abnormal white blood cell patterns, to indicate the need for further investigation. Other species capabilities are available.

Parameter	Description
HCT (haematocrit)	With every report
RBC (red blood cell count)	A vital supplement to the HCT Accurate measurements allow accurate calculations of MCH and MCHC.
HGB (haemoglobin)	With every report
RETIC , %RETIC (reticulocyte count, percentage of reticulocytes)	Reticulocytes are essential and the gold standard for characterising if an anaemia is regenerative or non-regenerative.
MCV (mean cell volume)	Serial measurement allows better monitoring of the progression/regression of a disease state.
RDW (red blood cell distribution width)	Objective measurement of variation in size of red blood cells (anisocytosis) Allows the veterinarian to better follow the progression and regression of a disease
MCHC (mean cell haemoglobin concentration)	With every report
MCH (mean cell haemoglobin)	With every report
PLT (platelet count)	The ProCyte Dx analyser offers a much more accurate platelet count than impedance-only counters
MPV, PDW, PCT (mean platelet volume, platelet distribution width, platelet haematocrit)	Aid in the characterisation of a platelet abnormality (such as presence or absence of a bone marrow response to a peripheral demand for platelets)
WBC (white blood cell count)	With every report
Monocytes and Lymphocytes (% and #)	Help identify inflammatory diseases where macrophages are a significant component of the inflammatory process Differentiation of monocytes and lymphocytes helps accurately identify the presence of an underlying glucocorticoid influences (e.g., stress, steroid administration, hyperadrenalcorticism)
Neutrophils (% and #)	Important in identifying certain types of inflammatory disease and their severity, as well as following the progression or regression of inflammation
Band Neutrophils	Noted when bands are suspected to be present in a sample. The presence of bands is the single best indicator of inflammation
Eosinophils (% and #)	Important in identifying systemic hypersensitivity, which can be caused by heartworm disease, flea bite dermatitis, feline asthma, allergic gastroenteritis and more The ProCyte Dx analyser identifies eosinophils for both canines and felines
Basophils (% and #)	May be helpful in identifying systemic hypersensitivity, as well as acute allergic reactions
nRBCs (nucleated red blood cells)	Noted when nRBCs are suspected to be present in a sample. nRBCs indicate bone marrow damage or extreme increases in red blood cell production, both of which prompt the doctor to act quickly.

Fluid Analysis	The ability to run body-fluid analyses for real-time cell counts and assistance in fluid classification
TNCC (total nucleated cell count)	A count of all nucleated cells in a body fluid, including white blood cells, nucleated red blood cells and both benign and malignant somatic cells, such as mesothelial cells, epithelial cells, etc.
Granulocyte (# and %)	Nucleated cells including all three granulocyte populations: neutrophils, eosinophils and basophils
Agranulocyte (# and %)	Nucleated cells including all nucleated cells not included in the “granulocyte” category: lymphocytes, monocytes, macrophages, mesothelial cells, neoplastic cells, etc.
RBC (red blood cell count)	A count of all non-nucleated red blood cell forms

Run a test in just three simple steps.

Enter the client and patient information on the IDEXX VetLab® Station.
Place the sample in the ProCyte Dx® analyser.
Tap the Run button and walk away.

That’s it!
Results are ready in just two minutes for next steps and sharing with clients in the IDEXX VetLab® Station diagnostic report during the patient visit.

Haematology and chemistry results in just eight minutes.

The ProCyte Dx analyser’s two-minute run time complements the speed of the Catalyst Dx™ Chemistry Analyser. Now, in just eight minutes, you can run in-depth chemistry and haematology diagnostic panels.

A Chem 22 and CBC with a five-part differential and absolute reticulocyte count in eight minutes
Four pre-anaesthetic panels, such as a Chem 10 and CBC, in just 18 minutes

Dot plots

Dot plots are a visual representation of the complete blood count (CBC); each dot represents a single cell. Dot plots are a critical element of the CBC, providing a snapshot of cellular morphology. Only the ProCyte Dx Haematology Analyser and the LaserCyte® Haematology Analyser provide these valuable tools.